Penn Medicine @Penn The Nobel Prize Katalin Kariko The Drew Weissman Lab UPenn should not brag about Dr. Kariko's extraordinary achievements until they apologize to her first... x.com/DrEricDing/sta…

Delightful to have friend and clinical luminary Mustafa Khasraw join us for Grand Rounds!

We're excited that our new study revealing fascinating functions for #neutrophils in #brain #cancers is now online at Cell

'The local microenvironment drives activation of neutrophils in human brain tumors'

#OpenAccess
Open for all to read 🔗: cell.com/cell/fulltext/…

Roel Verhaak I am fully supportive and personally advocate for the same whole heartedly -!one of the key strengths of the multi disciplinary nature !

CDKN2A mutations have equivalent prognostic significance to homozygous deletion in IDH-mutant astrocytoma academic.oup.com/jnen/article-a…

How about more PhDs in the SNO leadership? To reflect the 60% PhD membership? 🤔

Our transcript fusions portal tumorfusions.org made it into #NHS guidelines - happy that this project continues to be useful.

Great collab with Mario Suva Tirosh Lab Avishay Spitzer, MD, PhD Kevin Johnson #AntonioIavarone #AnnaLasorella #MasashiNomura #LucianoGarofano many others, with National Cancer Institute #projectCARE funding!

Fantastic to see first data coming out of #projectCARE , in which matched patient samples are compared at diagnosis and relapse, all by single cell RNAseq - fascinating! Pediatric #projectHOPE data following soon as well, stay tuned! NCI Division of Cancer Biology National Brain Tumor Society

What a fantastic talk by Roel Verhaak on “co-options of neural programs in recurrent GBM” at #EANO2023 .

Great molecular follow up talk in the session on how glioma cells co-opt neuronal programs by Roel Verhaak

A pleasure to present our work on CDKNA hemizygous deletions at #EANO2023 Uniklinikum Essen Uni Duisburg-Essen Hämatologie und Stammzelltransplantation, UK-Essen Yale University Yale UniversityMedicine Roel Verhaak Christian Reinhardt

Excellent talk by Emre Kocakavuk, MD, PhD on CDKN2A/B deletions in IDH-Mut gliomas at #EANO2023 . Great and important work on a very promising avenue for better prognostication in #glioma patients

Wonderful neurobiology keynote including his 2015 discovery of the brain lymphatic system (nature.com/articles/natur…) by Jonathan Kipnis #EANO2023

Genomics and epigenomics by Dr Roel Verhaak Roel Verhaak EANO #EANO2023 Evaluation of tumor and surrounding microenvironment changes in high grade gliomas over time via GLASS Consortium synapse.org/glass Yale Department of Neurosurgery

Primary brain tumours in adults - The Lancet thelancet.com/journals/lance…

Impressed by the scientifically sound and methodological approach of the Boundless Bio team (note my COI 👆): attacking the oncogenic cargo as well as the vehicle == synergy and cancer cell death! As we hypothesized years ago.

Meet Chris Bailey 👉 Specialist Registrar in #Haematology & Clinical Research Fellow at The Crick.

He told us about his work on #ecDNA & how this molecule challenges traditional models of #tumour evolution & drug resistance: bit.ly/3DAeIa4

#NPAW2023 | Chris Bailey

Boundless Bio
'Exploit the vulnerability of cancer cells with oncogenes amplified in their ecDNA.'
1. Circular Structure and Proto-oncogene Expression: Unlike the typical linear structure of chromosomal DNA, ecDNA is circular. The circular structure can lead to higher…

Looking forward to it!