AstraZeneca's ATM Inhibitor, Radiation Show Encouraging Signals in Two Early Brain Cancer Trials at #AACR24 precisionmedicineonline.com/precision-onco…

>90% inhibition of ATM in GBM samples from patients pre-op treated with AZD1390 at a range of doses. Powerful window-of-opportunity study from Nader Sanai Ivy Brain Tumor Center - incredibly useful for dose optimisation.

Unusually for GBM, phase 2-3 study will use the best dose! #btsm

Encouraging initial findings from Ivy Brain Tumor Center ‘s Phase 0/1b trial of AZD1390 as a radiation sensitizer in newly-diagnosed #GBM presented by Nader Sanai AACR #AACR2024

So excited to be part of this research on this novel SOD-mimic developed by Tovmasyan lab Ivy Brain Tumor Center in collaboration with An-Chi Tien with dual radiosenstizing and radio protection properties.

It was such a nostalgic experience to be back TIFR India where I started my research journey. Thank you Shubha Tole (she/her) for hosting me. It was great to learn about the exciting research on cell fate decisions in your lab and share what we do Ivy Brain Tumor Center BarrowNeurological

Thank you for the invitation to present Ivy Brain Tumor Center 's preclinical and clinical work @UMassneurosurg Grand Rounds Dr. Rachael Sirianni . I look forward to catching up with you and connecting with others at UMass later. BarrowNeurological #GBM #braincancer

One of the best moments as a mentor is to see your mentee succeed. So proud of my former graduate student Costanza Lo Cascio for receiving the Damon Runyon- St. Jude fellowship! #proudmentor

Our “Curries and Games” night was a hit again this year! It was great time to socialize with new lab members and James McNamara had the best games for us. We missed those who couldn’t make it and our alumni Connor White Costanza Lo Cascio Leo Elena Matt Dufault and Ernesto

What a great start to the Ivy Brain Tumor Center Seminar series with Dr. Graham’s talk on modeling of mutant histone-driven pediatric brain cancers.

Want to work with us this summer? Our Summer #UndergraduateInternship Program is accepting applications through Feb. 23! This paid internship offers the opportunity to work full time in a #neuroscience lab or other area of the Institute. Learn more/apply: bar.rw/3QCz3k6

Visit the 'whole tumor' data from Mathur et al, Cell, 2024 in a user friendly format: 3d-gbms.shinyapps.io/search/

and see Cell Leading Edge article by
Baig and Winkler, Cell, Jan 18, 2024
cell.com/cell/fulltext/…