We're looking forward to next week's episode with Dr. Ziyuan Guo (Ziyuan Guo) from Center for Stem Cell & Organoid Medicine! Check out his lab's Cell Stem Cell paper on #organoids to model the #BloodBrainBarrier: bit.ly/3YQCFWN

🔔 We're back with a brand new episode! Dr. Ziyuan Guo (Ziyuan Guo) from Center for Stem Cell & Organoid Medicine talks about his research on the #BloodBrainBarrier, in vivo reprogramming, and building better #organoids. Listen now: bit.ly/4dy3tiU

A nature study from The Fuchs lab identifies a surprising mechanism for removing dead cells: a tandem signaling process that turns ordinary cells into an efficient cleanup crew. #RockefellerScience rockefeller.edu/news/36351-sur…

We're very excited to welcome Dr. Ludovic Vallier (ludovic vallier) on our next episode! His lab uses #organoids to study liver development and disease. They recently published a nature paper on cellular plasticity in the liver. Read it here: go.nature.com/3SUfMOg

This week: #organoids to model #CeliacDisease! 🍞 Dr. António Santos and a team in Dr. Calvin Kuo's lab at Stanford Medicine generated air–liquid interface duodenal organoids that recapitulate gluten-dependent pathology. 📎: go.nature.com/4cQMJTE 🎧: bit.ly/4dy3tiU

#Organoids 🤝 #ImmuneCells! A team at Institute of Human Biology developed human intestinal immuno-organoids to study tissue-resident immune responses. Lauriane Cabon Gray Camp nature paper: go.nature.com/46UpRRd Discussion: bit.ly/4dy3tiU

Transplanted human pluripotent stem cell derived colonic organoid with E-CAD (white), CDX2 (red), SOX9 (green) and DAPI.

This week, we talk about a Nature Materials paper on naïve PSCs in the blastocyst! A team at @[email protected] designed a blastocyst motif substrate that reverts PSCs to a naïve state. #pluripotency Paper: go.nature.com/46QKspu Discussion: bit.ly/4dy3tiU

Our new paper on using engineered human cardiac tissues to study lupus-mediated myocardial injury is now out in Nature Cardiovascular Research! 🫀🔬 Congratulations to leads Sharon Fleischer 🎗️ & Trevor R. Nash & the team on this important study! nature.com/articles/s4416…

Our new study led by VFossati (she, her) & Paul Tesar is out in Cell Stem Cell! We report the largest collection of patient stem cell models of multiple sclerosis & use them to show that glial cells contribute to the disease, pointing to the need for new therapies: nyscf.org/resources/huma…

Our stem cell reprogramming experiment this August on International Space Station was a big team effort! 🚀 Here, NASA Astronauts Tracy Caldwell Dyson inserts a BioServe Space Technologies BioCell into the KEYENCE microscope on ISS. Inside are fibroblasts prepared by our team at Regenerative Medicine Institute at Cedars-Sinai,

Call us neurons, since we're excited about this paper! 🧠⚡ Drs. Husniye Kantarci & Pablo Elvira (Pablo Elvira) showed that #PGE2 is secreted by #SchwannCells and promotes neuronal excitability. @Du_Bois_Lab ZucheroLab 📄 - bit.ly/4dphTBM 🎧 - bit.ly/4g1XBzX

This month our Regenerative Medicine Seminar Series featured Joseph C Wu, MD, PhD from Stanford CVI who presented his lab’s studies of cardiovascular disease mechanisms and “clinical trials in a dish”.

#Gastruloids have many uses as #models for: early mammalian development, #SelfOrganization, mapping signalling/gene expression, morphogenesis. Here Lenne Lab use’m to develop gral tools to image gene/protein expression at diff scales biorxiv.org/content/10.110… #InNumbersWeTrust

Congratulations to Dr. Shuibing Chen (Shuibing Chen) on her lab's new Cell Stem Cell paper! Her team developed vascularized macrophage-islet #organoids to study damage from infection. Read the article: bit.ly/4gqAcJ1 Learn more about her work 👇 bit.ly/3MuyPex

🎉 Excited to share our latest study in @nature, showing that DNA🧬 #methylation is key to stemness in the adult #brain: nature.com/articles/s4158… A collaboration with Simon Anders, driven by Lukas PM Kremer and Santiago Cerrizuela. #epigenetics #neuroscience #singlecell. Pre-print summary 🧵👇

Check out the latest from Dr. Jun Wu's (Jun Wu Lab) lab! 👀 Dr. Emily Ballard (Emily Ballard) and the team developed a strategy to increase the #chimerism of human PSCs in mouse embryos. Cell Stem Cell paper: bit.ly/3yWmZ9T Discussion: bit.ly/3XvWyRy

This week: cellular communities in #aging & #Alzheimers 🧠 Dr. Gilad Sahar Green (Gilad Green) & a team at ELSC Brain & Columbia Medicine used single-nucleus #RNAseq to build an atlas of the aged prefrontal cortex. Article: go.nature.com/3yX7RJc Episode: bit.ly/4eaPLCr

Delighted to share the lab's latest preprint from ZIQI DONG Gurdon Institute showing an unexpected role for hypoxia in human lung differentiation: doi.org/10.1101/2024.0… Fabulous job working out the mechanisms Ziqi! Many thanks to our brilliant collaborators 😀