Amazing work presented by Mohamed Abazeed, MD, PhD at the #ESTRO24 spatial biology session

⚡SCLC cells have distinct transcriptional states

⚡states have differential susceptibility to chemo / ICPi

⚡SCLC cells switch states naturally & this is druggable

Northwestern

Our new analysis of ChatGPT’s performance answering rad onc patient questions, using both computational metrics + clinician evaluations! Highlights potential for AI LLMs to be integrated into the clinical workflow for patient education Lurie Cancer Center Northwestern Feinberg School of Medicine Mohamed Abazeed, MD, PhD

Congrats Sagnik Sarkar and Zhuoyang Zou for your excellent presentations @ #CoDEx 2024! Two new DNN models (toxicity prediction and lung cancer target segmentation) are coming to an information system near you.

A huge welcome to Jared, Abdul, & Andrew! We are so excited for you to join the Northwestern family! 🥳🙌 George E. Naoum, MD, MMSCI Shuhua (Steve) Zheng James Randall Amishi Bajaj, MD Eric Nesbit TaritaThomas MD, PhD, MBA Sean Sachdev, MD Mohamed Abazeed, MD, PhD Laila Gharzai MD LLM Jonathan Strauss Eric Donnelly Timothy Sita, MD, PhD

Excited to share our work showing the first validation of surrogate endpoints in HPV+ oropharyngeal cancer! We show that LRPFS, DMFS, and PFS correlate with 5yr OS. Important for trial design in this evolving dx space Michelle Mierzwa Matthew Schipper NRG Oncology

sciencedirect.com/science/articl…

Great to see this in print. Congrats Nadeem Riaz Nancy Lee and team!

January 18, 2024: The first AI-directed and personalized dose of radiotherapy. classic.clinicaltrials.gov/ct2/show/NCT05…

Dr. Quynh-Nhu Nguyen speaking on #sclc updates #NACLC23 and ongoing NRG studies on immunotherapy +/- consolidative RT and SWOG study on MRI surveillance vs. prophylactic cranial RT.

🔥🔥🔥 session with packed room at #NACLC23 !! HUGE thanks to Drs. Wozniak, Sen (Triparna Sen (Sen-Lab) ), Owonikoko (@teekayowo ) , Nguyen, Juloori (@ajuloorimd ) and Denise Rouse for teaching us about the state of the art in small cell lung carcinoma 🙏🏾

Great session on SCLC along the translational spectrum with an all star lineup: Taofeek K Owonikoko Triparna Sen (Sen-Lab) Aditya Juloori Sanjay Mukhopadhyay, Dr. Antoinette Wozniak, and Denise Rouse. #NACLC #IASLC

In next week's episode of the IASLC podcast, Lung Cancer Considered, Dr. Narjust Florez, MD, FASCO and I discuss the upcoming 2023 IASLC North America Conference on Lung Cancer #NACLC23 (December 1-3 in Chicago) with two of the co-chairs, Drs. Christine Bestvina and Mohamed Abazeed, MD, PhD. #LCSM

We are looking for a Thoracic Radiation Oncologist to join a fantastic team
careers.astro.org/job/thoracic-r…
-If you plan to be at ASTRO #ASTRO23 ACROresident please DM me

Excited to share our new pub reporting on a PI3K-AKT-mTOR gene expression signature predicting local failure and DFS after SBRT for early-stage #lungcancer (NSCLC). A job well done by Nikhil and team building on our preclinical data! #radbio #radonc #LCSM
acsjournals.onlinelibrary.wiley.com/doi/10.1002/cn…

I fear these are mere rationalizations. The RT + ICB paradigm is reeling (we’re chasing Goldie locks conditions with a much narrower window than expected). Moreover, paradigm that irradiating mets prevents new mets has poor foundation&without compelling/robust clinical evidence.

Had a great time at the AAP/ASCI/APSA JointMeeting this weekend! Thanks to APSA and Northwestern MSTP for the opportunity to share some research I’ve done with Mohamed Abazeed, MD, PhD and connect with inspiring colleagues & mentors. Looking forward to next year’s meeting!

Mohamed Abazeed, MD, PhD is currently presenting at #SCLC23 the topic: 'Multivalent State Transitions Shape the Intratumoral Composition of Small Cell Lung Carcinoma'. Memorial Sloan Kettering Cancer Center #lungcancer #LCSM

Delighted to share our most recent work investigating #aging after #WBRT , published in Neuro-0ncology SNO. Free access link: academic.oup.com/neuro-oncology…

First described by Dr. Abe Scopal, the abscopal effect is a wondrous mythical creature widely believed but rarely documented, like the unicorn. Still holding out hope though, did see a signal at #ASCO18 but always wonder when something seems so hard to prove how meaningful it is.