The doctor workforce is evolving, but instead of seeing this as a threat to workforce stability, the GMC says it could be an opportunity to reduce burnout and improve work-life balance #workforce

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Orkambi, Symkevi and Kaftrio are too expensive for NHS use despite being clinically effective for patients with cystic fibrosis, NICE has concluded #CFTRmodulators #cysticfibrosis

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Long-term treatment with #dupilumab is well tolerated and leads to persistent reductions in #asthma exacerbations and #steroid use in children, a study has shown

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Doctors should rethink the common practice of advising four-hourly maximum #salbutamol inhaler use in children discharged after an asthma attack, a group of experts has warned, calling the approach a “myth”

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Adagrasib has been approved by the UK’s MHRA as a treatment for KRAS G12C mutation-positive advanced #NSCLC

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Tobacco companies are using flavoured e-cigarettes as ‘adolescent training wheels’ to target their next generation of customers while circumventing advertising restrictions to reach millions around the world, experts say #vaping

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Professor James Chalmers tells us why respiratory care specialists can’t afford to miss this year’s BTS winter meeting James D Chalmers British Thoracic Society (BTS)

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Late-breaking abstracts presented at #ESMO23 show the promise of a new era of personalised, first-line lung cancer treatment based on targetable tumour mutations #lungcancer #NSCLC

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The combination of #pembrolizumab plus #lenvatinib shows promising anti-tumour activity, albeit with considerable toxicity, in patients with relapsed pleural #mesothelioma following chemotherapy

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UK registry data reveals that severe #asthma patients are more likely to achieve clinical #remission with #biologic therapy if they have a shorter disease duration, fewer comorbidities, and greater T2 inflammation

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Doctors have outlined “grave concerns” over the rapid advent of physician associates in the NHS and the related implications for patient safety, professional jurisdiction, liability and pay #NHS #workforce

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Adenocarcinoma is the most common histological subtype of lung cancer in the world, according to findings of a population-based study involving data from 185 different countries #lungcancer

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Increasing access to #CF TR modulators is bringing endocrine and metabolic issues to the fore and highlighting the need for ongoing multidisciplinary care in adults with cystic fibrosis #CF

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International guidelines on how to diagnose pulmonary #embolism have key similarities but also important areas of heterogeneity that highlight the need for a more standardised approach, researchers report

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Healthcare professionals have been reminded by the MHRA to alert their patients to the potential psychiatric side effects of #fluoroquinolones

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Respiratory physicians have compared the relatively new treatments #benralizumab and #mepolizumab for severe asthma in a real-world observational study, though UK experts believe the debate is far from settled

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Around 750,000 people in England have been misdiagnosed with #asthma , as a lack of access to simple tests in primary care is forcing GPs to make “educated guesses” on diagnoses, new research has revealed #spirometry #feno

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Identifying obstructive sleep apnoea patients according to endotypic traits can help guide therapy and improve outcomes #ERS2023 #OSA
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With a minimum follow-up now of 73 months, Checkmate 227 delivers more evidence for #nivolumab + #ipilimumab over chemotherapy in metastatic #NSCLC , regardless of PD-L1 expression

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Most patients with severe eosinophilic #asthma controlled on #benralizumab can significantly reduce their dose of inhaled corticosteroid without impacting asthma control, according to late-breaking research presented at ERS 2023

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