In our new study we chart human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution (RNA + ATAC) Cell authors.elsevier.com/sd/article/S00…

We are recruiting a senior research assistant (wet-lab) for my lab at Genome Institute of Singapore, apply here or email me for more information: careers.a-star.edu.sg/JobDetails.asp…

2nd Annual Single Cell symposium with Keynote Speaker Dr. Timothy Stuart! Tim Stuart Single Cell papers Single Cell Media

Johns Hopkins University, Turner Concourse
Sept. 29 & 30, 2022
Register today! allcounted.com/s?did=s14brril…

Curious why the nontransferred strand in Tn5 requires a 5' phosphate, this paper shows the (unexpected) answer beautifully academic.oup.com/nar/article/36…

Get your nb-Tn5 protein here!

I am happy to announce that NTT-seq plasmids are now available in Addgene. If you are interested in single-cell multifactorial chromatin profiling follow the link below and brew your nanobody-Tn5s🦙🧬 addgene.org/browse/article…

Check out NTT-seq for all your multimodal chromatin needs! an amazing collab with Raimondi Ivan NYGCtech: biorxiv.org/content/10.110…

Our new work, led by Marina Oliva, characterises unanticipated cellular complexity in plant roots, revealing an environmentally-responsive transcriptional state that modulates cell identities during root development
biorxiv.org/content/10.110…

Reaping single-cell information from single cells is a balance of data sparsity, cost and surprises. Hattie Chung Broad Genomics Tim Stuart NY Genome Center, Stephen Clark and Wulf Reik Babraham Institute, Roney S. Coimbra Fiocruz in English explain:
nature.com/articles/s4159…

Missarova, Rahul Satija, @marionilab & co present geneBasis, a method for identifying gene panels that capture the variability in single cell RNA-seq datasets, for further analysis. It doesn't require prior cell type annotation genomebiology.biomedcentral.com/articles/10.11…

We're excited to release a Human BioMolecular Atlas Program (HuBMAP) Azimuth reference of Human Bone Marrow - built using data from 39 donors - with high-resolution annotations of CD34+ lineage committed progenitors. Try a demo and map your own datasets at azimuth.hubmapconsortium.org

Our new preprint introducing scCUT&Tag-pro (single-cell profiling of histone modifications and cell surface proteins), scChromHMM (inferring chromatin states in single cells), and an integrated reference of 9 molecular modalities in human PBMC: biorxiv.org/content/10.110…

We used HiSeq 2500s for automated tissue staining and imaging — can’t wait to see what applications are next! NY Genome Center NYGCtech Kunal Pandit Silas Maniatis

We're hiring at Stanford Pathology! With research support from Parker Institute for Cancer Immunotherapy, National Human Genome Research Institute, and @Stanford Science Fellows, we are looking for a junior computational biologist to learn single-cell multi-omic analysis directly from me in the Ansu Satpathy lab careersearch.stanford.edu/jobs/life-scie…

Very excited to share geneBasis - an iterative approach to select an informative gene panel from your fave scRNA-seq data in an optimal manner. A thread below to briefly describe key points, and for those who do not mind TLDRs - biorxiv.org/content/10.110…. 1/n

I am recruiting a postdoc to work in stromal immunology of breast cancer. The project expands on our recent work doi.org/10.15252/embj.… and uses scRNA-Seq, scATA-Seq and spatial transcriptomics; ex vivo co-cultures and functional assays. DM or email for details. Please RT! 🤩