#Myeloma Paper of the Day: Study of immune fitness & teclistamab finds responders had higher baseline total T-cell counts, lower Tregs, fewer T-cells expressing co-inhibitory receptors, less soluble BCMA, and T-cell profile with more cytolytic potential: pubmed.ncbi.nlm.nih.gov/38657201/.

Carl Sagan explains how the ancient Greeks knew the Earth was round and calculated its circumference over 2,000 years ago.

Well done Ben nice job

Great job

Originally created by Arthur Shapiro and Alex Rose-Henig of American University, this illusion gives the overall impression that all of the movement involved is circular – but it's actually made by dots' straight motion

Worrying numbers for asct in mm ascopubs.org/doi/10.1200/JC…

Less than one month away! Bring it on NYU Grossman School of Medicine NYU Langone Health

Broke the winter break, first cycle ride out to Jones beach.

We don't yet have a way to guide therapy decisions with single-cell omics.

Taking one step forward to solve this, we developed a transfer learning method for patient stratification & resistance emergence to targeted therapies using sc-omics & validated in 3 trials. 🧵

Imp manuscript from the Mayo group Saurabh Zanwar showing the outcomes of pts w/ suboptimal response to DaraVCd in NDAL. I have traditionally switched to BCL2 inhibition ASAP if t(11;14) but for the rest such a tricky spot! Hopeful for TCE in this popn

nature.com/articles/s4137…

Great progress for myeloma patients

Last but not least Dr Freeman makes the case for Car T in the older age groups-it’s a wrap for iwMM 2024 great meeting thanks to everyone involved

This video produced for the Hubble travelling exhibition Our Place in Space, zooms from Venice out through the Solar System, the Milky Way, the Local Group and into the cosmic web.

And if you're feeling very small, that was the intent

IwMM day 2 kicks off with a discussion of Mezi and Altman

Boy done good!

I miss working with Niels

The t(4;14) surfaceome as a source of new targets in mm the role of cd70

A great panel discussion at #iwMyeloma24 with Francesco Maura, Kylee MacLachlan, Gareth Morgan, Yubao Wang, Lawrence Boise 🧬🔍

#HemOnc #MultipleMyeloma #Myeloma #MMsm

Dr Maclachlan presents results on biological differences in the genetics of mm in African Americans

Start of the iwMM Dr Landgren update on the successful ODAC for mrd as an end point for trials