A practice-changing study demonstrates a clear benefit for incorporating ibrutinib into induction and maintenance therapy for mantle cell lymphoma, writes Dr. Michael E. Williams. jwat.ch/3yICuSc

Original Article: Belantamab Mafodotin, Bortezomib, and Dexamethasone for Multiple Myeloma (DREAMM-7) nej.md/3wTS3pA

#ASCO24 | ASCO

What Predicts Phenoconversion from Pure Autonomic Failure to a Neurodegenerative Disease?

A natural history study identified clinical features that increased the risk for phenoconversion to an alpha-synucleinopathy in those with pure autonomic failure. jwat.ch/4aOpQOS

Ultraprocessed Food Intake and Adverse Cardiovascular Risk Profiles in Children

Consumption of pastries, cookies, and candy is associated with greater likelihood of high body-mass index and lower HDL cholesterol levels. jwat.ch/3x0nT41

#ProcessedFood

NEJM Group is reporting on cancer research news from #ASCO24 :
- Lorlatinib & advanced NSCLC
- Liver transplant + chemotherapy
- Enfortumab vedotin & advanced urothelial cancer
jwat.ch/3V7fXpC
Jyoti D Patel ILSON David

🧵 Weekend Briefing for June 1, 2024:

🆕 Images in Clinical Medicine: Small-Bowel Intussusception in an Adult nej.md/4c2pgxR

Does #aspirin help or worsen age-related macular degeneration? jwat.ch/3V4LRDf

Caring for Hospitalized Patients with Opioid Use Disorder:

A panel of experts lays out best practices and notes the challenges posed by the rise of illicit fentanyl. jwat.ch/3Vj8zca

#HospitalMedicine

More data support use of long-acting cabotegravir and rilpivirine in clinical practice for people with #HIV : jwat.ch/3V04M1Z

#IDTwitter Carlos del Rio

Andexanet decreases hematoma expansion for factor Xa inhibitor–associated intracerebral hemorrhage: jwat.ch/3yCshXB

NEJM

NEJM Group's clinician-guides Jyoti D Patel, ILSON David, Dr. Robert Dreicer, and Mikkael A. Sekeres MD, MS preview the upcoming #ASCO24 meeting. Hear what oncology results they're looking forward to: jwat.ch/3R6495I

Do GLP-1 agonists slow progression of renal disease in patients with type 2 diabetes? jwat.ch/3QYHZ5l

NEJM #diabetes #renaldisease

Are non-ID doctors better at providing primary care to people with HIV? Paul Sax takes a look in the latest HIV and ID Observations post. jwat.ch/3wRqHk2

#IDTwitter

“All-in-One” Therapy for Relapsed Acute Leukemia

In a pilot study, sequential anti-CD7 CAR T-cell infusion followed by haploidentical allogeneic hematopoietic stem-cell transplantation produced ongoing remission. jwat.ch/4dYkzXO

NEJM #leukemia

Beta-Blockers in Patients with COPD: A Randomized Trial jwat.ch/3KaULu1

In the Bridge–TIMI 73a trial, researchers assessed the efficacy and safety of olezarsen for lowering triglyceride levels in patients with moderate hypertriglyceridemia plus elevated cardiovascular risk and in those with severe hypertriglyceridemia. nej.md/3J8XIum

In new consensus guidance on arrhythmias in athletes, the focus is on return to play, if appropriate. jwat.ch/4dVxGsI Heart Rhythm Society

The American Gastroenterological Association provides expert guidance for diagnosing and managing cannabis hyperemesis syndrome. jwat.ch/4ay2nBe American Gastroenterological Association (AGA)

Dr. Allan Brett offers a primer on the drug vonoprazan, approved by the FDA in late 2023 for erosive esophagitis. jwat.ch/4btd8X7

The addition of the immune checkpoint inhibitor atezolizumab to chemotherapy fails to improve outcomes in anal cancer. jwat.ch/3yE8eHX

ILSON David #cancer