Study results suggest that video laryngoscopy may be a preferable approach for intubating patients undergoing surgical procedures.

ja.ma/3VnHpkP

Come and see our new website! The Outcomes Research Consortium includes more than 200 investigators in more than 25 countries.Outcomes Research Consortium
or.org

🤖🩺 Automating Anesthesia: Closed-Loop Systems Enhance Care: Better than manual control for stabilizing variables & reducing workload?

by Sean Coeckelenbergh et al. from Université Paris-Saclay 🇫🇷 and Outcomes Research Consortium 🇺🇸

link.springer.com/article/10.100…

see our interview at:

youtube.com/watch?v=zuj3B6…

A large trial with 3,000 patients tested the hypothesis that colchicine reduces the incidence of atrial fibrillation after noncardiac thoracic surgery. There was no significant effect on atrial fibrillation: 6.4% v. 7.5%, HR 0.85 (95% CI: 0.65, 1.1).

thelancet.com/journals/lance…

We’ve reached an important milestone. The Consortium has now published more than 2,000 full papers. To put 2,000 papers in perspective, it is comparable to every article in every issue of a journal like Anesthesiology for more than 15 years. Congratulations 💪

Vital sign abnormalities are common and often missed by routine intermittent assessments. Now we need trials explicitly comparing postoperative complications with continuous vs intermittent monitoring. --> wait for upcoming research from OutcomesRC 💪

cjgim.ca/index.php/csim…

An analysis of 8563 postoperative inpatients indicates, that patients only mobilize for about 4 minutes/h. Doubling mobilization time was associated with 25% fewer composite serious complications and shorter hospitalization.

jamanetwork.com/journals/jamas…

An analysis of > 14,000 patients reports distinct abnormalities in all vital signs in postsurgical patients on wards. As in previous reports, about half the abnormalities would have been missed with assessment of vital signs at 4-hour intervals.

sciencedirect.com/science/articl…

A major trial in which 2,900 patients having prolonged general surgery were randomized to intubation or a laryngeal mask airway --> There were significantly fewer minor complications with laryngeal mask airways.

…-publications.onlinelibrary.wiley.com/doi/10.1111/an…

Rest in Peace, Paolo Pelosi. Our deepest condolences.

Early mobilization after surgery matters! Results of a cohort study of 8653 patients having major surgery indicate that early mobilization was associated with a lower hazard for postoperative complications and shorter hospitalization.
JAMA Surgery

jamanetwork.com/journals/jamas…

BIG shoutout to 3 upcoming stars in anesthesiology. Drs. Elyad Ekrami, MD Stephania Paredes Padilla, MD and Mauro Bravo, the winners of the Anesthesiology Institute Research Day Cleveland Clinic Outcomes Research Consortium . Thank you for your great presentations of your research!

Another successful Anesthesiology Institute Research Day yesterday at CCF. Special thanks to Holger Klaus Eltzschig from UT Houston for his amazing and inspiring lecture.

Is sugammadex really better for pulmonary function?

In our new cohort study of 71,457 surgeries, postoperative minimum SpO2/FiO2 ratios in the PACU did not differ meaningfully after reversal of neuromuscular block by sugammadex or neostigmine.

Journal of Clinical Anesthesia Outcomes Research Consortium

🔓This new analysis demonstrates that neural networks can be trained to predict myocardial injury and death after non-cardiac surgery and death after non-cardiac surgery.

Prof Markus Schlaich Outcomes Research Consortium Ajmal Saeed Mian Clara Chow Nicholas Mills

🔗…-publications.onlinelibrary.wiley.com/doi/10.1111/an…

A recent RCT with 642 patients comparing dexmedetomidine v. placebo on delirium reports, that incidence of delirium was nearly identical in each group. However, AKI was slightly greater in patients given dexmedetomidine, possibly because of hypotension.

…-publications.onlinelibrary.wiley.com/doi/10.1111/an…

Growth Differentiation Factor 15 (GDF-15) is an excellent predictor of perioperative cardiovascular risk. It is far better than the RCRI and, and even better than the combination of RCRI and NT-ProBNP. GDF-15 should probably be used routinely.

pubs.asahq.org/anesthesiology…

Does a double-hit of postoperative anaemia and hypotension synergistically worsens 30-day composite of MI, mortality + AKI? -> lack of significant interaction suggests that effects of hypotension + anaemia are additive rather than multiplicative

DOI: 10.1097/EJA.0000000000001816

A pilot trial tested a novel pulse oximeter with an alert function: when saturation decreased, patients were given a verbal prompt followed by a mild electric shock --> the alert system halved the amount of in-hospital saturation.

DOI: 10.1111/aas.14193