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Enamine is resuming work. Please review the new statement from our Founder and CEO, Andrey Tolmachev. bit.ly/3KkVeIq

1/ How do proteins take their shape in the cell? Insights from our article with Jack Kelly Yue Lab at Newcastle University of Oxford Ville Paavilainen 🇫🇮🇺🇦 @HiLIFE_Helsinki lotta happonen Lund University VIB_StructuralBiologyBrussels Imperial College London Pfizer Inc. nature.com/articles/s4159… #OpenAccess 🧵👇

Finally found time to read the paper beyond quickly browsing through it. I'm afraid my disbelief has only increased. Apart from specific technical points, if a paper is questioning long and widely held beliefs that appear to be supported by lots of observations, one would 1/n

Often a major scientific discovery can be boiled down to a #singleplot in a paper. Mullis & Faloona describe "polymerase-catalyzed chain reaction". We did this paper in 1st year journal club Rockefeller University and concluded that nobody would ever use this method #PCR PMID: 3431465

Our review in memoriam Danny Tawfik is out: Phenotypic mutations contribute to protein diversity and shape protein evolution onlinelibrary.wiley.com/doi/10.1002/pr… MPI-CBG Dresden Center for Systems Biology Dresden

People are asking me about the origins of and key milestones in the timeline of #bioorthogonal chemistry, so here is a quick summary. 1/n

A historic failure

#FreeBook Retweet to enter raffle to receive a free copy of The World by S Sebag Montefiore Winner announced on Nov 7th One of our Books of the Year. W&N #freebooks #freebies #historylovers

Excited that Foghorn Therapeutics has opened the Phase 1 trial of their BRD9 degrader FHD-609 to patients with poorly differentiated chordoma based on preclinical data generated through the Chordoma Foundation Drug Screening Program clinicaltrials.gov/ct2/show/NCT04…

Just gonna leave this right here…

one small consolation of turning 60 this year is the ability to submit to 𝘔𝘈𝘛𝘜𝘙𝘌 family journals — sure they’re low impact (for our knees) but they have an early bird special if you submit between 4:00 and 5:30 on weekdays

This is the moment Mars peeked out from behind our moon after being hidden for an hour. This shot was captured using my largest telescope and a special high-speed camera. Seeing another planet rising on the horizon of our moon was such a surreal experience.

For decades, Dr. Anthony Fauci has led with science to fight infectious disease. His leadership during the pandemic saved countless lives, & his commitment to evidence-based science is a key reason why public policies have been able to protect public health. ASM stands w/ Fauci.

Science ran a big experiment on itself for the last ~60 years. It didn't work out. experimentalhistory.substack.com/p/the-rise-and…

It is with heavy hearts that we announce the passing of our beloved colleague and friend, C. David Allis. Aside from his groundbreaking contributions to biomedical science, David will be remembered for his warmth, humility, and relentless optimism.

Here is a ~ 42 kDa cryo-EM map (~3.4  Å). Initially, we thought we had a nice map of our target protein. But it turns out the protein is MBP :( At least, you can clearly see the maltose :P

What's the role of Moesin (MSN) and CD44 in Alzheimer's? The SGC-Oxford-Emory-UNC teams have developed some reagents to explore this interaction. biorxiv.org/content/10.110…

OPERATIONAL UPDATE: Debunking Hamas fake news with IDF Spokesperson @JConricus. x.com/i/broadcasts/1…

Must-read speech on the legality of Israel's fight against Hamas, delivered in 🇬🇧 House of Lords yesterday by Lord Guglielmo Verdirame KC, professor and barrister in public international law: “There has been a lot of talk about proportionality in the law on self-defence. I refer

It's almost four weeks since the horrific terrorist attack on #Israel. A lot has happened, the public debate has become heated and confused. Find thoughts from Vice-Chancellor Robert #Habeck in the video, putting the events in context. 📣With English, Hebrew and Arabic subtitles.