Michel Chedid El Helou, MD, MSc discusses sex differences in the performance of the transthyretin amyloid cardiomyopathy (ATTR CM) risk score @ #ACC24 🫀

Cleveland Clinic CCF Cardiology Fellows

#ACC24 Day 1 at the #HeartFailure poster session, I had the honor to present our work on the use of GDMT in patients with #LVAD .

Key Takeaway:

➡️ There is significant opportunity to improve the use of GDMT in LVAD patients!

Trejeeve (Tre) Martyn Phoo Cleveland Clinic Heart, Vascular & Thoracic

Today, Verve Therapeutics is announcing updates to our PCSK9 program:

1. voluntarily pausing enrollment in the Heart-1 trail of VERVE-101
2. prioritizing clinical development of VERVE-102 which uses a different LNP delivery system
3. announcing clinical trial application have been cleared

Thrilled by our UC San Francisco internal medicine match! Fab students from 27 schools (UCSF 10, Harvard 5, UCLA/Yale/UChic/UWash 4 each). 28% ID as UIM; 19% MD-PhDs. Thx Rebecca Berman, residency leaders & staff, and our residents, who create the culture. Pics: List (L) & Zoom toast (R)

Round of applause for all our speakers and everyone who participated in our lively discussion at today’s focus meeting👏🏻

Lots of promising developments in the pipeline from #AI use in endpoint adjudication to voice technology
#Heartfailure #clinicaltrials #CardioTwitter

HFC Special Focus meeting starting now…

Christopher O'Connor Mona Fiuzat Harlan Krumholz Sneha Shah Jain, MD, MBA setting the stage for the meeting with the importance of #AI and how the HF community can embrace this groundbreaking technology

NUMBER GO UP on Last Week Tonight!

Thanks AHA Science for the opportunity to lead this & a HUGE 🙏🏻to this ⭐️🫶🏻⭐️team Jason N. Katz Shashank Sinha, MD, MSc, FACC, FAHA Maryjane Farr MD MSc, FACC FAST FHFSA FAHA Tracy Wang Christopher Barnett MD, MPH, FACC Jennifer Cowger Abdulla A. Damluji, MD, PhD Colleen McIlvennan

Special shout out to Manreet Kanwar Paul St Laurent, DNP, RN 🏳️‍🌈 for their unwavering ♥️&support🙏🏻

In this #clusterRCT of 2495 ppl 🏥for #HF
🔺 #transitional (including 🏠 visits & long-term #HF clinics), did not ⬇️ composite ☠️, 🏥, 🚑 at 3y
🔺likely because #GDMT uptake didn’t meaningfully⬆️
🔺risk HIGHER than invasive cancers: >50%☠️ at 3y
doi.org/10.1002/ejhf.3…
👏 Tauben Averbuch MD

28% of Black patients had wild-type transthyretin amyloidosis, not V122I. As such, using genotype first approach to dictate further work up would miss q in 3-4 patients.
#ATTR #Cardiotwitter

Our study probing at the question of racial disparities vs genotype in patients with #ATTR #amyloid V122I is finally out. Thank you to my incredible mentor Mazen Hanna and amazing co-authors Josh Saef Pieter Martens Trejeeve (Tre) Martyn Jerry Estep W. H. Wilson Tang, MD

ajconline.org/article/S0002-…

HRS mourns the loss of Past President and pioneer in the field of cardiac EP, Bruce Wilkoff, MD, FHRS, CCDS. He dedicated his career to preventing sudden death, but his contributions to the field are immeasurable. Among his many honors and accomplishments, Dr. Wilkoff was

#Nudges are all around us. Leveraging #behavorialsci 4 health using scalable, existing dissemination platforms may drive #pophealth . In partnership with @CIRL_DK Tor Biering-Sørensen, MD, MSc, MPH, PhD, we highlight NEJM Evidence the 🇩🇰 #NUDGEtrial concept, a series of nationwide #impsci studies 4 health

In European Society of Cardiology Journals we describe how provider factors outweigh patient factors in the use of comprehensive GDMT utilizing an EHR-embedded GDMT score Jerry Estep Lucy West Josh Saef CCF Cardiology Fellows Jessica Hohman Cleveland Clinic Heart, Vascular & Thoracic Umesh Khot W. H. Wilson Tang, MD Randall Starling onlinelibrary.wiley.com/doi/10.1002/ej…

HAPPY MATCH DAY! We are so excited to announce the CCF Cardiology Class of 2027! 🥳🎊🎉 They are truly the best of the best. Welcome to the #CCFCardsFam !

venu menon Samir Kapadia Lars Svensson Ran Lee Shady Nakhla Michael Faulx, MD, FACC

Exciting time attending the #AHA2023 in a charming Philly, and reconnecting with many colleagues and friends!

I had the honor to present our findings Cleveland Clinic Heart, Vascular & Thoracic with Trejeeve (Tre) Martyn.

Key takeaway: Efforts to scale ATTR-CM risk prediction should be mindful of racial differences!

Welcome, Dr. Benjamin Zorach to Southcoast Health! Dr. Zorach is our new Structural and Interventional Cardiologist at the Heart Center. You can learn More about Dr. Zorach, his specialties and the procedures he performs at southcoast.org/doctors/benjam….

Mentor, friend, supporter when I was down and out. You never forget when someone has your back when you’ were at your lowest. Congrats ⁦⁦Randall Starling⁩ for your lifetime achievement award. Well deserved.

Great to discuss lived experiences and future directions of #ImpSci with a this group @ZaraLatif5 Ankeet S. Bhatt, MD, MBA BiykemBozkurt F. Perry Wilson, MD MSCE HFSA thanks for organizing Mitchell Psotka Growing role for #transparency around resourcing, less noisy alerts, & qualitative methods Cleveland Clinic Heart, Vascular & Thoracic

(1/11) The U.S. FDA has denied the sNDA for #patisiran for an indication for #ATTR -CM, based on the APOLLO-B trial. 😮One can respect the process but disagree with the result -- and I think this was a major miss by U.S. FDA. A brief🧵... #amyloidosis businesswire.com/news/home/2023…