NEW Review🎉👉Composition and functions of bacterial membrane vesicles Eberl & colleagues discuss the different types of bacterial membrane vesicle, how they are formed, their structure and composition and their diverse functions. rdcu.be/c7Sxd

We are excited to share our latest preprint on the genomic characterization of the anti-phage arsenal of Actinobacteria, where we reveal unique characteristics of this overlooked phylum (for instance, the absence of 1/3 of known defense systems 🤯) (1/9) biorxiv.org/content/10.110…

Causing trouble at the KNVM meeting ⁦Véronique⁩ ⁦Janine Liedtke⁩ ⁦Maarten Lubbers⁩ ⁦@xiaobo_zhong⁩ ⁦Marjolein Crooijmans⁩ ⁦Noortje Dannenberg⁩ ⁦Adam Sidi Mabrouk⁩ Renée Kapteijn, PhD⁩ KNVM⁩ ⁦

So many novel antiphage systems out there! Hard to keep up with the pace of discoveries? We reviewed for Nature Reviews Microbiology the highly diverse antiphage defence systems of bacteria; from molecular mechanisms to evolutionary drivers of such diversity. rdcu.be/dg3ql

Could not resist. Making that figure in 2019, I thought the newly uncovered diversity of antiphage systems was already incredible. We now know it was just the tip of the iceberg. I hope our new review will help people dive into this wonderful field. rdcu.be/dg3ql.

Phages infecting protoplasts Bacteriophages phi29 attaching, infecting & replicating in Bacillus subtilis protoplasts by Véronique Ongenae (Véronique), Universiteit Leiden 🔬Titan Krios transmission electron microscope (#TEM), Netherlands Center for Electron Nanoscopy (NeCEN), Leiden

Here it is the best #phage therapy I ever read! A monumental achievement by Jean-Paul Pirnay et al. 100 PT cases w/clinical improvement in 77% difficult-to-treat infections. The big conclusion "phages make antibiotics great again!" Happy to contribute!💯 medrxiv.org/content/10.110…

Happy to share our new preprint! We used viperins🐍, to understand the conservation and diversification of immune genes across domains of life. A deep dive in the evolutionary history of immune genes shared by prokaryotes and eukaryotes! biorxiv.org/cgi/content/sh…

Really glad to finally share my 1st baby from my post-doc 🥲 Aude Bernheim and I have been obsessed with viperins for a while, so we decided to trace their incredible story, from LUCA to #asgard #archaea, to #eukaryotes. Even more fun: we did it in colab with my dear friend Fabai Wu Lab

We have an open PhD position in the lab focusing on "Bacterial antiviral immunity" - looking forward to welcome more phage enthusiasts in our group! New Concepts in Prokaryotic Virus-Host Interaction , Forschungszentrum Jülich | @[email protected] , Heinrich-Heine-Universität Düsseldorf Feel free to contact me via email, in case you have any questions. fz-juelich.de/de/karriere/st…

Thank you for inviting me! It was a pleasure😁

Lab retreat!

I am excited to share this work with you! We show that conidia (asexual spores) accumulate trehalose and mannitol during the spore maturation process. Conidia lacking these compatible solutes are extremely heat sensitive (16 orders of magnitude!!). (1/6) doi.org/10.1186/s40694…

So proud of my bachelor students Vera van Neer and Annabel Kempff, who described two new phage species in our paper that got published today!! 🎊👏 doi.org/10.1038/s41598…

Phage fibers and spikes: a nanoscale Swiss army knife for host infection - ScienceDirect sciencedirect.com/science/articl…

As result of a public outreach with New Concepts in Prokaryotic Virus-Host Interaction, engaging with local schools, we here present five novel Streptomyces phages infecting S. griseus, S. olivaceus and S. venezuelae. May the phage be with you. DFG public | @[email protected], Forschungszentrum Jülich | @[email protected], Heinrich-Heine-Universität Düsseldorf biorxiv.org/content/10.110…

Clinical strains of Pseudomonas aeruginosa have accumulated phage defense systems in their genome matching their broad resistance to diverse phage families. Great work by Rita, Daan and Jelger. Ana Rita Costa, Daan F van den Berg science.org/doi/10.1126/sc…

🚨Super excited to share our pre-print describing how we used genomics to discover a family of anti-phage lanthipeptides from Actinobacteria 🦠 This marks a significant expansion in the number of bacterial natural products involved in chemical defense. A thread 👇: MDMLab

Excited to share our latest paper on new Eukaryotic-like bacteriophage defense systems. What great joint project by Daan F van den Berg, Ana Rita Costa and Jelger Esser combining the power of bioinformatics and experiments. sciencedirect.com/science/articl…

Shared evolutionary roots for viral defense. Daan F van den Berg Ana Rita Costa & Esser Stan Brouns discover bacterial homologs of eukaryotic antiviral defenses and demonstrate the anti-phage activity for six previously uncharacterized systems cell.com/cell-host-micr…