'Constricting Life Space and Likelihood of Neurodegenerative Disease in Community-Dwelling Older Men' (JAMA NO 2023) - 'clinician assessments of life space or wearable electronics may help identify older adults at risk of cognitive decline' - jamanetwork.com/journals/jaman…

'Baclofen and the risk of fall and fracture in older adults: A real-world cohort study' (JAGS 2023) - agsjournals.onlinelibrary.wiley.com/doi/10.1111/jg…

'Breaking the Cycle: Using Serious Illness Communication to Optimize Care Transition Planning in Serious Illness' (JAMDA 2023) - Many older Americans nearing the end of life are “rehabbed to death” - sciencedirect.com/science/articl…

'Algorithmic Fairness of Machine Learning Models for Alzheimer Disease Progression' (JAMA NO 2023) - 'machine learning models had notable deficits in fairness across race and ethnicity groups' - jamanetwork.com/journals/jaman…

'Demographic characteristics of participants in clinical trials to treat Alzheimer disease, 2008–2023' (JAGS 2023) - 'Clinical trials of drugs to treat AD enrolled participants who were not representative of the Medicare FFS population' - agsjournals.onlinelibrary.wiley.com/doi/10.1111/jg…

'Brexpiprazole for the Treatment of Agitation in Alzheimer Dementia' (JAMA Neuro 2023) - 'Brexpiprazole, 2 or 3 mg, reduced agitation in AD and was generally well tolerated over 12 weeks.' jamanetwork.com/journals/jaman…

'The Natural History of Disability and Caregiving Before and After Long-Term Care Entry' (JAMA IM 2023) - 'Data may help clinicians understand when home supports approach a breaking point and appraise LTC options' - jamanetwork.com/journals/jamai…

'Lecanemab Safety in Clarity AD Open-Label Extension, Including Subcutaneous Formulation' - 'Lecanemab SC may provide substantial benefit for greater patient access, improved compliance and convenience with overall lower costs to healthcare system'🤔- eisai.com/ir/library/pre…

'Increasing illness severity of skilled nursing facility patients over time: Implications for readmission penalties' (JAGS 2023) - 'SNF quality metrics and incentives/penalties need to be revised to reflect the current acuity level of patients' - agsjournals.onlinelibrary.wiley.com/doi/10.1111/jg…

'The Syndrome of Inappropriate Antidiuresis' (NEJM 2023) - '40% of older (>65 years of age) inpatients have hyponatremia, with 25 to 40% of cases attributed to SIAD' - nejm.org/doi/full/10.10…

'A New Framework for Dementia Nomenclature' (JAMA Neurology 2023) - 'framework clearly separating the clinical syndromic presentation experienced by affected individuals from possible underlying pathophysiologies' - jamanetwork.com/journals/jaman…

'Changes in Care Use and Financial Status Associated With Dementia in Older Adults' (JAMA IM 2023) - 'Family care availability should be accounted for in a comprehensive assessment of predicting the effects of dementia' - jamanetwork.com/journals/jamai…

'Eligibility rates among racially and ethnically diverse US participants in Phase 2 and Phase 3 RCTs of lecanemab and elenbecestat in early Alzheimer's disease' (2023) - onlinelibrary.wiley.com/doi/10.1002/an…

'Association Between Timing of Clinical Evaluation by a Physician or Advanced Practitioner and Risk of Rehospitalization in Older Adults Admitted to a Skilled Nursing Facility Following Hospitalization' (JAMDA 2023) - sciencedirect.com/science/articl…

'Predicting sojourn times across dementia disease stages, institutionalization, and mortality' (A&D 2023) - 'Full disease course from MCI to institutionalized severe dementia lasted between 6.2 and 10.1 years' - alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

'Would You Screen This Patient for Cognitive Impairment?' (Annals 2023) - acpjournals.org/doi/10.7326/M2…

'Call to action: a five nations consensus on the use of intravenous zoledronate after hip fracture' (2023) - 'We invite all those looking after patients with hip fracture to ask not ‘should I give IV Zol?’, but ‘why wouldn’t I give IV Zol?’' - academic.oup.com/ageing/article…

Study suggests that clinicians may not be selectively targeting colorectal cancer screening to a small subset of healthy older adults with long life expectancies who may benefit from continued screening. ja.ma/44CNV8p

Dr. James Deardorff, Kaiwei Lu, Bocheng Jing, Sun Jeon, Dr. John Boscardin, Kathy Fung, and Dr. sei published a research letter in JAMA: 'Frequency of Screening for Colorectal Cancer by Predicted Life Expectancy Among Adults 76-85 Years' jamanetwork.com/journals/jama/…

'Safety of Switching from a VKA to a NOAC in Frail Older Patients with Atrial Fibrillation: Results of the FRAIL-AF RCT' (Circulation 2023) - 'associated with more bleeding complications compared to continuing VKA treatment' - ahajournals.org/doi/10.1161/CI…