Glad to share our latest work: Structural variation cooperates with permissive chromatin to control enhancer hijacking-mediated oncogenic transcription, Blood Journal by Giovanni, Yuannyu Jian Xu Children’s Research Institute at UT Southwestern St. Jude Research Jian Zhou Lyda Hill Department of Bioinformatics
doi.org/10.1182/blood.…

Cracking the regulatory code: We have genomes for 1000s of species, but ENCODE only for 2 – what do we do? Natural language models have shown that syntax and semantics can be learned from text alone. Can we do the same for genomes?⬇️
biorxiv.org/content/10.110…

🚨Postdoc position available🚨. We investigate the role of transcriptional condensates in development and disease. We combine biochemistry, microscopy, and epigenomics to study condensate function. Please connect if you are interested. Please RT. tinyurl.com/2p8upxt5

Thrilled to share our last method - TruEst - about estimating genome rearrangement evolutionary distance between species (rdcu.be/dgrlM). Work done by Alexey Zabelkin, me, and Nikita Alexeev. Random graphs, Fuss–Catalan numbers, and more cool things in a thread:

We have two postdoc openings (until filled): (1) general computational genomics & machine learning and (2) ALS genomics funded by MND Association. Please DM me if you are interested in either of them, and help spread it if you know someone would be interested. Application links:👇

Our latest paper - now published in its final form Nature Genetics - examines long-standing questions about enhancer-promoter communication.
nature.com/articles/s4158…

A brief thread with the key results is below.

🔬🧬 Excited to share our latest study science.org/doi/10.1126/sc… Science Magazine developing ChromExM which uses expansion microscopy to visualize the chromatin,
transcription, RNA POL II and pioneer factor Nanog during genome activation.

I'm super excited to host Charlie Boone for a seminar next week!

The Boone lab has done amazing work to systematically characterize genetic interactions using huge arrayed libraries of yeast mutants.

If you're at UTSW, the talk will be Tues. 6/20 - 4pm!

Glad to share our new work by Pavel Avdeyev & co! If you are still looking for a diffusion generative model naturally designed for discrete categorical data like biological sequence, we have a new method w/ app. to sudoku solving and promoter design.

Check this out at #ICML23

How do subnuclear compartments relate to gene expression and 3D genome organization in single cells? Our new preprint presents two-layer DNA seqFISH+ imaging method to map over 100,000 genomic loci, 17,856 introns, mRNAs, and antibodies in single cells. biorxiv.org/content/10.110…

The Summer Undergraduate Research Fellowship (SURF) and Amgen Scholars Program is one of my favorite UTSW programs. I’m excited about the incoming 2023 class and highly recommend undergraduate students to apply for next year. UTSW Graduate School of Biomedical Sciences Dr. Arnaldo Díaz Vázquez

utsouthwestern.edu/education/grad…

We need to talk about how the China Initiative affects the US postdoc shortage (aka not just a problem for 1 ethnicity):

1. Senior Chinese American scientists forced to return to China = postdocs no longer need to leave home for world-class training

🧵
science.org/content/articl…

North Texas friends: Join us for Careers in Computational Biology next Friday (Mar 3) 1PM. I'll be speaking along with a great line up of women in comp bio including Minerva Cordero, Katherine Hoadley, Aleks Nielsen and Paniz Karbasi!!! Lyda Hill Department of Bioinformatics
UTSW Computational Biology

Postdoctoral Research Fellow in Computational Biology Jian Zhou

Computational biology postdoc opportunity with Jian Zhou lab. Join us @ UTSW (zhoulab.io)

jobrxiv.org/job/ut-southwe…

#ScienceJobs #job
Dallas #UnitedStatesUS #Postdocto ...
jobrxiv.org/job/ut-southwe…

Postdoc position available in the Strand lab. NIH funded, warm climate and great food in Dallas, travel opportunities, cutting-edge techniques, human tissue research with high translational potential. Come join us!

Thinking about grad school? Consider our Biomedical engineering graduate program! Our graduate track in computational biology includes fantastic classes in software development, machine learning and mathematics. Plus diverse research opportunities in clinical and basic science!

Undergraduate competition application window still open! Come join us for a great day of computational biology and bioinformatics at UT Southwestern. Please spread the word!

各位校友，我们非常荣幸地邀请您参加第十一届北京大学北美生物医学年会暨北大生科北美校友年会！本次活动将于2022年11月5日在UTSW举行。我们年会的网站链接在：pkubio.org/dallas2022/
我们热忱邀请北大生科校友，北大其他院系生物医学相关行业的校友，以及所有对生物医学有兴趣的朋友参加本次聚会!