PHOSP-COVID study 😊👇

❤️ Long Covid Support 🌍 & we're so grateful to be partners with you all ❤️ so mindful of your time and effort ⚖️ when unwell
👏 Felicity Liew Peter Openshaw Rhyan Thwaites 👏
🌟 now to turn data into more therapeutic clinical trials & reverse the pathophysiology
🤞 we're planning BIG 🤞

Subtypes of #LongCovid indicating specific immune/inflammation markers and pathways related to principal symptoms
nature.com/articles/s4159…
Nature Immunology by Felicity Liew Claudia Efstathiou Peter Openshaw Ryan Thwaites and their collaborators across the UK

Long Covid Support 🌍 PHOSP-COVID study Nikki S. Natalie Rogers 😷 Claire Hastie 💙 Rachael Evans Linzy Houchen-Wolloff Important to note that this was a cohort of hospitalised patients only, so might not be applicable to LC patients who had milder initial infections.

'This week, ONS data reconfirmed the substantial impact this is having on our national prosperity. The number of people who cannot work primarily because of long-term illness reached yet another record, at nearly 2.6 million.' We must invest in better health.

This is looking like a variant that is not fizzling out. Everyone taking it very seriously (including WHO and national agencies around the world).

Key thing is to get some data as soon as possible on its immune evasion and severity .

CDC update: 20% #LongCovid
'As more persons are exposed to and infected by SARS-CoV-2, reports of patients who experience persistent symptoms or organ dysfunction after acute COVID-19 and develop post-COVID conditions have increased' cdc.gov/mmwr/volumes/7…

Great editorial on #LongCovid by Felicity Liew and Peter Openshaw - discussing our recent study and the urgent need to understand this disease better and develop treatments:
NHLI UoM Biology, Medicine and Health Lydia Becker Institute

erj.ersjournals.com/content/early/…

Each week, I republish my articles from Forbes on my website to make them available to read for free. You can now read articles published during the month of January.

For current listings, visit williamhaseltine.com/writings

There's the moral argument for increasing nurses' pay - very strong. Then, there's the economic argument. Want to fill all those vacant nurses' posts? Pay a decent wage, and relieve the pressures of understaffed services.

Nurses' pay has fallen by 5% since 2010. The pay offer will lead to a predicted further fall of 5%. The PM describes this as 'appropriate and fair'!! nuffieldtrust.org.uk/resource/chart…

Our latest work using PHOSP-COVID study and ISARIC4C data, showing that first-line nasal IgA defenses are induced after #Covid_19 , last 9 months but are not boosted by IM #vaccines . Co-led by Peter Openshaw Ryan Thwaites and Lance Turtle. Link here👇🏻 eBioMedicine – The Lancet Discovery Science

Why we desperately need nasal vaccines to block infections and reinfections
thelancet.com/journals/ebiom… eBioMedicine – The Lancet Discovery Science by Felicity Liew Shubha Talwar and colleagues

Out recently: doi.org/10.1111/imm.13…, the most extensive profiling of complement in infectious disease.
The alternative pathway drives uncontrolled complement activation in COVID-19, which is predictive of outcome, and suggests tissue deposition is important in pathology (1/4)