The Spring 2024 edition of the Ludwig Link is live! Check it out for a deep dive into a 3-year initiative focused on immunometabolism, a Q&A with three early-career scientists, and our usual round up of science, awards and news from Ludwig researchers. bit.ly/ll24s

🥳 Le Fonds Baillet Latour célèbre également ses 50 ans cette année. Dans son discours, la Reine a salué le travail de l’organisation et ses recherches dans différents domaines.
🔗 Lisez son discours intégral : bit.ly/4diZO8L.

🙌 Hier, la Reine a remis le Baillet Latour Biomedical Award au Dr. Jingjing Zhu du de Duve Institute (@UCLouvain_be) pour ses recherches en matière d'immunothérapie des tumeurs.

Our congratulations to Ludwig Princeton University Associate Director Eileen P. White, PhD on her election to the American Academy of Arts & Sciences for her many landmark contributions to cancer biology and ongoing work in the field. Learn more about her life and career: bit.ly/3DD8ILr

Such a wonderful visit to Oxford - so many stimulating discussions with amazing students and faculty!

Many thanks to you all at ⁦Ludwig Cancer⁩ ⁦University of Oxford⁩ 😊

A fantastic (as always) talk today at our seminar series by Johanna Joyce, hosted by the Ludwig Cancer University of Oxford . Really inspiring and thought provoking work with ideas that could be applied to all cancers 🔬😍 #CancerResearch

Ludwig Lausanne #scientists identify and show how to target a key #tumor #defense against #immune #attack
newswise.com/articles/ludwi…
Ludwig Cancer

💡NEW study by Alizee Grimm Matteo Morotti Denada Dangaj George Coukos et al., in nature
📈high levels of Prostaglandin E2 in tumors undermine the anti-cancer immune response and compromises TIL-ACT
➡️nature.com/articles/s4158…
Université de Lausanne CHUV / Centre hospitalier universitaire vaudois Ludwig Cancer TU München

💡NEW study by Pierpaolo Ginefra, Vannini Lab and colleagues, Cancer Research Communications AACR
🌰Read this fascinating study on the promising potential of #Urolithin -A in boosting cancer immunosurveillance!
➡️shorturl.at/gCX26
Ludwig Cancer CHUV / Centre hospitalier universitaire vaudois Université de Lausanne NestléHealthScience

Today is a special day. Our multi-year study led by an AMAZING group of scientists Mariko Takahashi, Harrison Chong and Siwen Zhang comes out Cell. DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Check it out here: authors.elsevier.com/a/1izTCL7PXqQHi.

Interested in #spatial analyses of complex tissues - incl the tumor #microenvironment ?

Then check out our #HIFI paper - you can get stunning images like these 🤩 with 40+ markers by sequential IF - paired with a powerful #analysis pipeline!

Watson et al:
nature.com/articles/s4146…

Team led by Ludwig Oncology UNIL CHUV's Matteo Morotti, Alizee Grimm, Denarda Dangaj & George Coukos reports in Nature a new mechanism of immune evasion employed by tumors & shows how it can be disabled to improve the efficacy of a cancer immunotherapy. bit.ly/4aFpF9n

Ludwig Oncology UNIL CHUV's Spencer S Watson & Johanna Joyce developed HIFI, an open-source method to simultaneously capture the dynamic structural & cellular architecture of tumors & used it to analyze changes in brain tumors subjected to radiotherapy: rdcu.be/dELus

📢📢Excited to share that my work Vannini Lab has been published in Cancer Research Communications 📢📢 Here we investigated the effect of the natural compound Urolithin-A on CD8+ T cells! A short tweetorial

💡NEW study by GiancarloCroce , David Gfeller et al., in Nature Communications
🤖 AI: a powerful ally to understand the immune sytem!
GfellerLab developed #MixTCRpred , a deep-learning tool that analyzes big datasets of TCRs.
➡️shorturl.at/fijvZ
Ludwig Cancer Université de Lausanne CHUV / Centre hospitalier universitaire vaudois

💡NEW study by Spencer S Watson Johanna Joyce et al., in Nature Communications
🧠Glioblastoma vs. brain metastasis show unique responses to radiation therapy 🩻

Ludwig Cancer Université de Lausanne CHUV / Centre hospitalier universitaire vaudois Johanna Joyce Lab
➡️ #OpenAccess : rdcu.be/dELus

Excited to share our new platform for hyperplexed IF spatial imaging & analysis - HIFI!

We developed this to be as #accessible & economical as possible for all interested in #spatial analysis of complex tissues

nature.com/articles/s4146…
#OpenAccess : rdcu.be/dELus

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Day4 #AACR24 so happy to present my work on lung cancer persister evolution trajectories to KRAS inhibitor. Got some wonderful discussions. Thanks to support from sponsors: Amgen, NCI F32 Fellowship and Ludwig Cancer research foundation.

🧾Read our Q&A with Johanna Joyce, newly elected as a Fellow of the AACR Academy, 2024!
➡️full text: shorturl.at/hkZ39
🏆Congrats again!

Ludwig Cancer Université de Lausanne Faculté de biologie et de médecine (inactif) CHUV / Centre hospitalier universitaire vaudois Johanna Joyce Lab
#CancerResearch

Ludwig Stanford Medicine's Zinaida Good (@GoodZinaida) discussed at #AACR24 exciting research on a type of immunotherapy in a poster titled, 'Lineage tracing defines responding CAR T cells in patients with B cell malignancies.'