Congratulations all around!!!

UChicago has been showing the way for years. Universities should adopt their Chicago Statement on freedom of expression and the Kalven principles on institutional neutrality. Admins make their lives so. much. easier. with these in place. @uchicago The Chicago Forum for Free Inquiry and Expression

Causal inference on high-dimensional biological data is right up my alley, so decided to journal club this conference paper from Martin R. Oliver Stegle Kai Ueltzhöffer.
Have lots of ❓s and a few thoughts. But some context first..:

We introduce an ARG-inspired data structure Genotype Representation Graph (GRG) to enable lossless data compression, efficient computation through graph traversal. Developed a fast inference method. Cost ~80 GBP to convert 350TB VCF (200,000 UKBiobank WGS) into 160 GB GRG.

A lot of people at sitting at the peak of mount stupid right now. Let me add some minimally politicized complexity so that you can join me in the valley of despair, or maybe even the slope of enlightenment.

Judaism is ancient. Let's start way back to the story of Abraham /1

I’m a scholar of the Israeli-Palestinian conflict and a longtime advocate for peace and for Palestinian rights. I have publicly opposed Israel’s occupation of the West Bank, and its blockade and now destruction of Gaza. I support the rights of students and faculty to peacefully

Some of you know I've spent the past ~20 years looking for ways to apply #AgingBiology to improve health (dramatically). Five years ago, what I've learned drove me to start Gordian Biotechnology with Francisco LePort, as a way to cut through biological complexity. Today we're starting to share

Congratulations Naomi Pierce of Museum of Comparative Zoology, newly inducted #NASmember ! #NAS161 #evolutionarybiology #zoology

1/ Had a few minutes before the faculty meeting yesterday so I stopped by the Harvard Yard encampment. An interesting mix: a bunch of people quietly hanging out and listening to a teach-in lecture, amid handmade signs glorifying violence and urging the destruction of Israel

עד שכל החטופים חוזרים הביתה ועד שממשלת החורבן לוקחת אחריות ומכריזה על בחירות, אין ברירה וחייבים להמשיך להפגין. בואו.

Breaking: The MAGA Supreme Court majority appears ready to rule that the right to 'life, liberty, and the pursuit of happiness' doesn't extend to women with pregnancy complications or who otherwise need abortions.

This is horrifying, and it is because of Donald Trump.

Very honored to be among the new elected members of the American Academy of Arts and Sciences. This is a testament to the dedication, creativity and hard work of past and current lab members. Incredibly grateful to all of them.

Dmitri Petrov 💔 Don't know, but there is a posted RNAlater recipe here: protocols.io/view/RNAlater-…

Do people know what RNA/DNA shield actually is? Asking for a friend.

How do we predict the statistical associations between mutations that spontaneously emerge in an evolving population? Excited to share some new work w/ Zhiru Liu and Benjamin Good that approaches this question!

We find evidence that Harbin, Dali, and Kabwe are likely Denisovans or their close kin! Using gene regulation, which predicts traits with >85% accuracy, we scanned the fossil record and found a remarkable fit to predicted Denisovan anatomy. See🧵👇 biorxiv.org/content/10.110…

The first phase of mutations in an experimental #evolution project impacted multiple traits, while later mutations were more specific, impacting individual traits🧬

These findings suggest a transition from early, wide-reaching mutations to more targeted ones🎯

#science #bio

Congrats to Grant Kinsler, Yuping Li, Gavin Sherlock, & Dmitri Petrov 💔!!🥳🥳

Read the full manuscript here
biorxiv.org/content/10.110…

Thanks for reading the thread! There’s more in the manuscript than I can cover in the 🧵so check it out and let us know what you think! Thanks again to Yuping Li Gavin Sherlock Dmitri Petrov 💔 for all their support, insight, and help in making this project happen! n/n

Super excited about this work! Curious what people think!