Post- #ESTRO24 . Urquhart Castle 🏰 overlooking Loch Ness 🏴󠁧󠁢󠁳󠁣󠁴󠁿

Anna, you’ve been a spectacularly good ESTRO President - thank you for your commitment and inspiration.

Design and main results:
🚩MDT vs ENRT, both arms 6mo of ADT
🚩Higher GU2+ tox in ENRT arm, but mainly due to more prostate bed RT in this arm
🚩Omitting PB RT results in higher rate of local failures
🚩Locoregional control superior with ENRT: 90% control @ 3yr.
🏴MFS not mature

Huge endeavour by ESTRO ESMO - Eur. Oncology to create guidelines for combination of #radiotherapy & new cancer drugs.

Looking forward to full paper. As Dr. David Palma discussed, the toxicity threshold to withhold #radiotherapy (or lower dose) needs to be defined on case by case basis.

Great presentation at #ismrm 2024 in Singapore by Vall d’Hebron Institute of Oncology (VHIO) Radiomics Group 's Anna Voronova -- her new FlowSim simulator enables the estimation of #microvascular properties in #cancer , and may enable the computation of new biomarkers in tumours. Well done Anna!!

Congratulations to @ESTRO Anna Kirby Anthony Chalmers 💙 for a record-breaking, breathtaking, stimulating, earth-shaking #ESTRO2024 . Enjoyed Scotland, the hospitality, the networking, and all the science. 🙏🏽🏴󠁧󠁢󠁳󠁣󠁴󠁿🙏🏽🏴󠁧󠁢󠁳󠁣󠁴󠁿

So proud of Priyanka P who did a fantastic job presenting the results of the TRAP trial at #ESTRO24 , funded by Prostate Cancer UK SBRT can delay time to next therapy (usually chemotherapy in this setting) maintaining QOL. Thanks to collaborators across the UK

MRI scans may help reduce unnecessary biopsies & diagnose more aggressive cancers.
✅ A meta-analysis of over 80,000 men found MRI led to:
⭕️Fewer biopsies overall (down to 28%)
⭕️Less detection of slow-growing cancers
⭕️Similar detection of high-risk cancers
👉This could mean…

#ESTRO24 Piet Ost presenting outcomes of STORM randomized Ph II of MDT v ENRT for oligorecurrent prostate cancer #pcsm

✅ ENRT ⬆️BRFS, LRFS

MDT a/w 8-fold ⬆️ nodal recurrence 3➡️25%

Omitting PB ⬆️ local recurrences 3-fold (5➡️14%), but also increases GU2+ toxicity

12 years after we launched ORATOR, what did we learn?
Three summary slides 👇👇👇

Well done Alison Tree 💙🇺🇦 excellent presentation of the acute tox results from #PACE C

Anthony Chalmers 💙 receives the #ESTRO24 Interdisciplinary Award - a life of multidisciplinary collaboration. 👏🏽👏🏽👏🏽🤩 An emotional moment, indeed. ESTRO The Royal College of Radiologists

⚡️SABR for oligoprogressive mCRPC on ARPI

TRAP trial for #ProstateCancer presented by Priyanka Patel

Encouraging results in phase I. Next up: STAR-TRAP phase II RCT

The ICR Alison Tree 💙🇺🇦

Cédric Dralauns with results of hypo-FLAME #ESTRO24 ESTRO

Low toxicity with focal RT boost in SBRT. Excellent outcomes. #radonc #ProstateCancer

PACE-C acute toxicity results: SBRT vs moderate hypofrac #ESTRO24
Alison Tree 💙🇺🇦 ESTRO #radonc #ProstateCancer

#ProstateCancer : Dissemination and availability of minimally invasive treatments to underserved populations. Presentation by SamWashUro UCSFUrology. #AUA24 written coverage by Julian Chavarriaga University of Toronto > bit.ly/3WpiTjP Amer. Urol. Assn.

ORATOR2 study OS and PFS - David Palma
#ESTRO24

Did not go this far but a quick 🏃 Tyler Seibert MD PhD style around the city and it was pretty nice too!

Good way to relax after great #ESTRO24 sessions

Taking a break from #ESTRO24 for afternoon hike