Brandie Leach
@bhealdleach
Oncology Clinical Program Manager at Invitae. Former GC at Cleveland Clinic. Passionate about hereditary GI cancer 🧬. ☕️ lover. Opinions are my own.
ID:3533630176
03-09-2015 11:41:50
341 Tweet
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For Day 3⃣ of #hereditarycancerweek , we are highlighting Juvenile polyposis syndrome (JPS)
➡️JPS is a #HereditaryGICancer syndrome in which individuals have multiple polyps in the stomach & colon w/ increased risk for stomach/colon cancers
👉Learn more tinyurl.com/3mstwfxu
PGV prevalence similar in <50 & >=50 yrs, supports #universal #germline #genetictesting all #patients w/ #uterinecancer #endometrialcancer c/w UnitedHealthcare medical policy Brandie Leach Invitae @GynOncJnls
#access #germline testing #precisionmedicine #precisiontherapy #clinicaltrials
#ASCO22 platform preview- #germline #genetictesting in >30,000 #colorectalcancer #patients , stratified by ancestry. 99% of positive #patients had PGVs w/ #precisiontherapy #clinicaltrial & management implications
Brandie Leach et al. Invitae
meetings.asco.org/abstracts-pres…
What proportion of pathogenic germline variants in different genes would you find if you did germline testing in all patients with GI cancers? Heather Hampel
ascopubs.org/doi/figure/10.…
The Stand Up To Cancer GENERATE study was able to get ~90% uptake of cascade testing among individuals with hereditary pancreatic cancer. Great work Sapna Syngal, MD and team #DDW2022
Learning from Sapna Syngal, MD at #DDW2022 There are many genes associated with hereditary pancreatic cancer. All patients with #pancreaticcancer should have #genetictesting
The Meeting Planning Committee is working hard to ensure a successful #InSiGHT2022 with a high-quality program and an exciting social agenda!
Meet the committee led by Matthew Kalady and Brandie Leach here👉 bit.ly/3jUx247
Excited to see all the great research #hereditarycrc experts have been up to! Matthew Kalady Swati G. Patel, MD MS Carol Burke Peter Stanich, MD Heather Hampel David Liska Andy Latchford Dr Ian Frayling 🇺🇦 #LongCovid Sir John Burn Sonia Kupfer Mohammad Ali Abbass #lynchsyndrome #FAP #hereditarypancca
Pashtoon Kasi MD, MS ASCO OncoAlert Mark Lewis Manju George MVSc PhD Rectal Cancer Survivor Dr Joseph McCollom DO Shaalan Beg Sakti Chakrabarti, MD Vivek Subbiah, MD Sam Klempner Aparna Raj Parikh Mike Thompson, MD, PhD, FASCO Toni Choueiri, MD Effect of adjuvant chemo persists also across stages if ctDNA+, from high risk stage II to IV
Still #freetoaccess until the 31 May 2020: bit.ly/2wJfQts
#hereditarycoloncancer #colorectalcancer #polyposis #familialcancer #lynchsyndrome #positionstatement
Matt Yurgelun, MD Brandie Leach Sonia Kupfer Heather Hampel @drmikesageneYES Nancy You Maureen Mork Jessica Stoll
For those working in GI oncology, listen to this podcast with Brandie Leach talking about the CGA-IGC position statement on multi-gene testing for #coloncancer and then read the paper. Would love thoughts about our recommendations. cga-igc.podomatic.com