ORG. one has reached a major milestone — successfully completing the assembly of 90 critically endangered species. This marks the end of its pilot phase, with the project now partnering with New England Biolabs to further boost global conservation efforts.

Read: bit.ly/4buo9Hi

Reveal more biology.

Ahmad Abou Tayoun & team unveil a new method to identify risk mutations for spinal muscular atrophy (SMA). Their method has the potential to replace current extensive testing cascades & improve SMA outcomes in the future.

Read: bit.ly/44v6Kfh #WYMM

At #nanoporeconf , Gil Kogan will discuss sequencing 100+ research samples of individual's with early onset and familial Parkinson's disease who previously had a negative whole exome sequencing result.

What you're missing matters. #WYMM

Register here: bit.ly/3UklhFQ

Is Oxford Nanopore duplex basecalling beneficial for bacterial genome assembly? I did some tests, and it seems like it might be!

New blog post here:
rrwick.github.io/2024/05/08/dup…

Stay on top of what's next. This months publications picks include:
Uncovering the critical role of telomeres
The potential to improve IVF
Precise identification of imprinting disorders
Combating agricultural and ecological threats
and more...

Read: bit.ly/3UOylVi

It's not 'difficile' to identify this microbe anymore.

Read how Rhys White 🧬 & team identified a ward-based outbreak of Clostridioides difficile that would have otherwise gone undetected, using #nanopore technology.

Excited to present our latest Oxford Nanopore liquid biopsy paper! Here, we generate the first long-read survey of circulating DNA in patients with a diverse set of cancer types. Short 🧵 follows ... [1/5]

biorxiv.org/content/10.110…

Out with the old. In with the future.

Join Sophia Gibson at #nanoporeconf to discover their groundbreaking preliminary results from re-sequencing the The 1000 Genomes Project cohort. Plus, experience interactive ways to explore their data!

Register here: bit.ly/3JGUBKm

This webinar will highlight nanopore sequencing as a comprehensive and sensitive QC method for rAAVs evaluation — which is supporting internal research activities at AstraZeneca.

Learn more: bit.ly/4b1iBnI

What you're missing matters #WYMM

Don't miss Hannah Titheradge at this year's #nanopore conf . She'll discuss the transformative potential of #nanopore sequencing for resolving rare genetic disorders.

Register to attend online here: bit.ly/4blyvJe

At #nanoporeconf , Lauren Lui will share her research on the unseen microbes of the ocean and their influence on global health. Join her as she explores how these discoveries could reshape our approach to environmental monitoring.

Learn more: bit.ly/44pdTgS

Join Mrinalini Watsa at the #nanoporeconf as she shares how her team are using nanopore technology to solve conservation problems from the Kenyan Savannah to the Peruvian Amazon.

Learn more: bit.ly/4bk8YQP

In-person tickets are sold out. Join us online for free.

More. Better. With less.

Discover how nanopore technology can help to unlock better gene therapies by ensuring high-quality rAAV preparations and confirming correct genome packaging.

Learn more: bit.ly/3y6Cprd

What you're missing matters #WYMM

Thanks KAUST Research for highlighting our genome editing work. Stay tuned for more interesting finding in follow up studies. Baolei Yuan Oxford Nanopore Altos Labs discovery.kaust.edu.sa/en/article/244… discovery.kaust.edu.sa/en/article/244…

The Nanopore Community Meeting is going to Boston this September!

If you've got some research you'd like to share with the Community, submit your abstract here: bit.ly/4dnHf3u #nanoporeconf

Excited for #nanoporeconf ? Don't miss Mike Clark as he explores the role of isoforms in brain development using nanopore single-cell RNA sequencing. Join Mark online for his 5th appearance to hear the latest cutting-edge genomics.

Register here: bit.ly/4a72gwm

What you're missing matters. Come see for yourself!

At #nanoporeconf , Alexander Wittenberg will discuss constructing high-quality, chromosome scale, fully phased, reference pan-genomes, & breeding new varieties of fungal resistant plants.

Attend online for free: bit.ly/4a4RF5g

RNA sequencing is routinely used to analyse isoforms as part of biomarker discovery, yet most methods fail to represent isoform diversity.

Learn how nanopore sequencing overcomes this challenge by capturing entire isoforms, in single reads.

Learn more: bit.ly/4aZknpr

We have released some raw Oxford Nanopore data for benchmarking purposes, along with some basecalled outputs.

We use the subset of 20k or 500k for benchmarking tools and methods a LOT!

We thought they would be helpful to others too.

4/5kHz R10.4.1 & RNA004

gentechgp.github.io/gtgseq/

Viruses don’t sleep so why should we? Midnight sequencing protocols 🦠🧬 #H5 #HPAI #Viromics #Alaska #LondonCalling Oxford Nanopore UAA BioSciences ARTIC Network