Photos from Danish military; largest surface disturbance is 1 km diameter!

Apparently the Nord Stream 1 & 2 pipelines have developed not one, not two, but three large holes, just off the coast of south Sweden. Interesting technical thread below. Is that the world’s smallest violin I hear playing a sad tune for Russian gas exports?

How are the hundreds of copies of mitochondrial DNA packaged in our cells? It’s a mystery because histones and chromatin factors are not in mitochondria and the high copy number presents challenges! Read what Stefan Stefan Isaac found in our preprint. (1/7)
biorxiv.org/content/10.110…

Haplotype-aware analysis of somatic copy number variations from single -cell transcriptomes go.nature.com/3CbknU6

Waking up to good news!

In October 2021 medicine laureate Ardem Patapoutian and his son Luca, woke up to discover that Ardem had become a Nobel Prize laureate for his work investigating how our bodies recognise touch.

Who will wake up to good news this year?

Photo: Nancy Hong

Not long until the 2022 medicine laureates are revealed - have you told your friends? Join the excitement here!

Watch the live stream and hear the news first at nobelprize.org and right here The Nobel Prize: twitter.com/i/broadcasts/1…

#NobelPrize

To my knowledge, this is the first study leading to some sensible gene candidates for ME/CFS, a ”debilitating chronic disease that lacks known pathogenesis, distinctive diagnostic criteria, and effective treatment options”. A glimmer of hope for patients? Replication needed obvs

Tweetorial by Lars Borm

Very happy that our EEL method for large scale, high resolution spatial transcriptome profiling is out now! Thanks to all who contributed to this fun project! Especially Sten Linnarsson simone codeluppi Alejandro Mossi Camiel Mannens Jokubas Janusauskas

Jens Hjerling Leffler ⭐️⭐️ Sten Linnarsson Samples are so overrated.

Scalable in situ single-cell profiling by electrophoretic capture of mRNA using EEL FISH go.nature.com/3r4svzm

Just like that, it’s out!

Failure of human rhombic lip differentiation underlies medulloblastoma formation nature.com/articles/s4158… && Unified rhombic lip origins of group 3 and group 4 medulloblastoma nature.com/articles/s4158…

Great @naturebiotech publication demonstrating both 3’ and 5’ scRNA-seq as well as Perturb-seq on @ultimagenomics sequencer: nature.com/articles/s4158….
Congrats to Sean Simmons, Xian Adiconis, Gila Yanai, Joshua Levin, Aviv Regev, and everyone involved.
#singlecell #sequencing

A zombie snail

It's been taken over by a parasite controlling its motor functions & eye stalks, mimicking caterpillars. The parasitic worm wants the snail to be eaten by birds, in whose intestines it will reproduce

[read more: buff.ly/2ro2Nap]

Fractal spirographs are generated by tracking a series of circles rotating around each other as shown in this animation by PantheraLeo1359531

[source: buff.ly/3LcfOf7]

The University of Chicago, Department of Human Genetics, is searching for a new computational faculty.
apply.interfolio.com/112673
We are a small, friendly department doing top-quality science. Come join us! (Please RT)

UCSF is hiring new Neuroscience faculty! If you study addiction, neuromodulation, or related brain circuitry, we'd love to see your application for this position: aprecruit.ucsf.edu/JPF04147

Ouch