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A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation ( Vujkovic et al.) go.nature.com/3GLHOUF

Today is my first day as an Assistant Professor of Nutrition Science at Penn Nursing Penn- I am beyond thrilled to continue my research on #NAFLD and metabolic diseases and expanding into some exciting new areas as well! #firstgen #NewPI

I’m gonna live forever ☕️

We're hiring! Immediate opening for a research technician for lipid metabolism and #NAFLD projects bit.ly/3WnITce And a postdoc (R01-funded) working with human iPSC on #lipidomics and #AlzheimersDisease co-mentored with Dan Rader at Penn Genetics bit.ly/3FUSMZc

🧬Just published!Our study reveals MTTP I128T reduces hepatic steatosis AND plasma lipids.Promising target to reduce hepatic and circulating lipids! Kai Markus Schneider Kate Townsend Creasy (she/her) Marijana Vujković Helen Huang Eleonora Scorletti MD PhD Inuk Zandvakili MD PhD Uniklinik RWTH AC roypounder.apt bit.ly/43s2s6u (1/5)

💊Are we underestimating statins? Our study of 1.7M participants suggests they might prevent liver diseases!👇 Kai Markus Schneider Rohit Loomba Arunkumar Krishnan Kirk Wangensteen, MD/PhD Jonel Trebicka Kate Townsend Creasy (she/her) Eleonora Scorletti MD PhD Marijana Vujković Inuk Zandvakili MD PhD JAMA Network Open (1/10) tinyurl.com/2avxu53z

📢 Exciting news! 🎉 Omega-3 supplementation may prevent liver diseases, a study led by our own Mara Vell. 🌟 #LiverHealth 📚 Read the full study here: doi.org/10.3389/fpubh.… (1/5) Kai Markus Schneider

An email from the first summer student to join my independent lab: "This has been an incredibly valuable experience for me, and you've been an outstanding mentor..." the lows are low, but the highs... 🥹

Statin use is associated with hepatoprotective effects among men, individuals with diabetes, and patients at genetic risk for liver disease. Study in JAMA Network Open. Rohit Loomba Arunkumar Krishnan Carolin V. Schneider, MD Kirk Wangensteen, MD/PhD Kate Townsend Creasy (she/her) Eleonora Scorletti MD PhD fal.cn/3AmvC

Paper aler📢 Using #NaturalLanguageProcessing, we mined 4.85M reports from Penn Medicine EHR, revealing a striking underdiagnosis of MASLD. (1/5) doi.org/10.1016/j.ecli… Kai Markus Schneider Marina Serper, MD, MS Rotonya Carr Kirk Wangensteen, MD/PhD Marijana Vujković Inuk Zandvakili MD PhD Kate Townsend Creasy (she/her) Eleonora Scorletti MD PhD Helen Huang

⚡️NEW OPIOID VIRAL TOOL⚡️ Lead by Greg Salimando, Ph.D. in collab with Karl Deisseroth We developed a catalog of mu-opioid receptor promoters (MORp) for viral access to endogenous opioid-expressing cell types 🦠🧠🐁🐀🐒 nature.com/articles/s4146… 🧵for more info on use & where to order:

📣 New paper in Hepatology Communications, led by Mara Vell, exploring the hepatoprotective effects of #aspirin. We've uncovered important sex-specific implications! (1/7) tinyurl.com/mubxdyrp Kai Markus Schneider Eleonora Scorletti MD PhD Kate Townsend Creasy (she/her) Kirk Wangensteen, MD/PhD Marina Serper, MD, MS Arunkumar Krishnan Marijana Vujković

🔬🚨 We published a new study JHEP Reports: "A missense variant in PLIN2 Ser251Pro Reduces Hepatic Steatosis in Mice" jhep-reports.eu/article/S2589-… Carolin V. Schneider, MD Rotonya Carr Kate Townsend Creasy (she/her) Sookyoung Jeon Delfin Gerard Buyco Marijana Vujković Nick Hand, PhD Clementina Mesaros Marie Guerraty MD, PhD Yedidya Saiman

Great collaboration! Rotonya Carr Carolin V. Schneider, MD Delfin Gerard Buyco Kate Townsend Creasy (she/her) Nick Hand, PhD Sookyoung Jeon Marijana Vujković Emma Elizabeth Furth Marie Guerraty MD, PhD

This project was such a labor of love and I'm happy to have it published- exciting role for long chain fatty acids in liver development and regeneration via cell cycle regulation

🧠⚡️Ecstatic to share our preprint – Mimicking opioid analgesia in cortical pain circuits biorxiv.org/cgi/content/sh… Covering cingulate cell-types for pain + morphine pain-relief, a non-addictive gene therapy for chronic pain & our deep-learning pain behavior platform: LUPE 🧵

📢Hot off the press: Think you know everything about TM6SF2? Meet ERLIN1! doi.org/10.1016/j.medj… Great study by our excellent student Miriam Rendel with Cecilia Vitali Kate Townsend Creasy (she/her) David Zhang Eleonora Scorletti MD PhD Helen Huang Joe Park, MD, PhD Mara Vell Kai Markus Schneider (1/3)

Excited to share our aMASLDing research on how machine learning uncovered dietary manganese might protect against hepatic steatosis. #LiverHealth #MASLD (1/10) Kate Townsend Creasy (she/her) Kai Markus Schneider Jan Clusmann Rohit Loomba Tom Luedde onlinelibrary.wiley.com/doi/10.1111/li…