Happy to share our collaborative preprint with Albert Giralt (Giralt lab) and Ruediger Klein. We show that Yamanaka factors induction expand the cortex and enhance cognitive skills. Moreover, their induction protect against neurodegeneration in a mouse model of AD. biorxiv.org/content/10.110…

Excited to announce a major medical milestone today with Mass General Surgery, as we announced the first ever transplantation of a genetically engineered porcine kidney into a living human recipient. 🧬🧬

Read our release:
shorturl.at/kEGTV

Huge breakthrough! First ever in the history of the Universe 🏆🏆🏆
The magnificent Dodo bird is resurrected! 
The New York Times where are you?
#DeExtinction Figure 1:

The first 'mammoth' looks kinda unhealthy 🤔

The Colossal Biosciences® elephant iPSC preprint has been updated twice in a week, with each update I’m less and less convinced they have derived iPSC #EleFunFactFriday

biorxiv.org/content/10.110…

Our Matters Arising preprint highlights the following issues with the Transient Naive Treatment (TNT) method for improved generation of human iPSCs published nature :
1. Characterization of bulk iPSCs rather than clonal iPSC lines;
2. Persistent Sendai virus expression in most…

Sendai virus persistence questions the transient naive reprogramming method for iPSC generation biorxiv.org/cgi/content/sh… #bioRxiv

And in the roundup:

1) A GENtoniK cocktail 🍸
Emiliano Hergenreder Lorenz Center for Stem Cell Biology at Sloan Kettering

2) Pancreatic organoids ♋️
Weill Cornell Medicine Surgery Cell Stem Cell

3) Mammary organoids 🧫
NCI Center for Cancer Research Developmental Cell

4) Chimeric super-SOX 🧦
Sergiy Velychko Caitlin M. MacCarthy

Weekly reads: game of clones, super-SOX, Moonwalk Bio, Great Wall’s living skin ipscell.com/2024/01/weekly… #stemcells

Happy New Year! We're ringing in 2024 with lots of great papers and an exciting Reviews series on the Hallmarks of Stem Cells! Check out the flagship Review from Hans Clevers & Joep Beumer on Hallmarks of stemness in mammalian tissues. More to come! cell.com/cell-stem-cell…