Ready to go for poster #2!
Come by 12-1.30 if you would like to know more about our clinical case series on Legionella longbeachae, an under-diagnosed cause of severe pneumonia
(P4145- section B row 15 position 24).
NUH_Micro Annie Joseph
#ECCMID2024
#ECCMIDglobal2024

🇮🇪☘️Ireland looking a good option.

Interesting to see the use of echinocandins in UTI, reflecting v limited options actually available for this.

Antifungal pipeline doesn't look great for candida UTI either (big problem where I am!)

Anyone use nitroxaline? Has C.auris activity but limited data 🤔

CALL TO ACTION: I need all of your help.
There is a black box warning on low dose vaginal estrogen (VE) products. See below. It states, 'warning: endometrial cancer, cardiovascular disorders, probable dementia.' Low dose VE has NEVER been show to cause any of the above.

🆕️🔥Fantastic review 🌟 by 🌟s
Russell Lewis Matteo Bassetti
David Denning
Triazole antifungal drug interactions—practical considerations for excellent prescribing #IDXposts academic.oup.com/jac/article-ab…

🆕️⚡️The ‘Ten Commandments’ for the 2023 European Society of Cardiology guidelines for the management of endocarditis⚡️ #IDXposts
academic.oup.com/eurheartj/adva…

If patients aren’t quickly getting subglottic suction tubes (within 48 hours) after TBI evidence is pretty strong for stat ceftriaxone sciencedirect.com/science/articl…

Q: Why do you disagree with the IDSA GN infection Guidelines re ampC?

GN Guidelines cite PMID 29566147 as rationale for the following statement: S marcescens, Morganella morganii, and Providencia spp., are unlikely to overexpress ampC based on both in vitro analysis
1/x

pubmed.ncbi.nlm.nih.gov/29566147/
the purpose of the study was to determine the frequency in which these pathogens mutated from wild time (not induced) to de-repressed.
Results based on counting triangles in Fig 1.

Invasive fungal infections in transplant recipients

➡️factors influencing the pathogenesis
➡️timing after SOT and HSCT

doi.org/10.1016/j.bj.2…

🆕️🔥Double blind Randomized Clinical Trial JAMA Internal Medicine
99 primary care centers in the UK
Daily d-mannose did not reduce the proportion of women with recurrent UTI in primary care who experienced a subsequent clinically suspected UTI #IDXposts
jamanetwork.com/journals/jamai…

One of the greatest frauds perpetrated by the NHS is getting away with calling a 48-hour working week “full time” and a normal 40-hour week “less than full time”

Great session on Infections in Urology at ESIU - EAU Section of Infections in Urology session: PCNL poses infection risks. Tailoring antibiotic prophylaxis/therapy based on infection risk is crucial
#eau24 zafer tandogdu Prof Bhaskar Somani Policlinico di Milano

The escalating resistance of M.pneumoniae to macrolides has become a concern
🆕️🔥Systematic review & network meta-analysis
Effectiveness and safety of tetracyclines [eg doxycycline, minocycline] & quinolones in people with Mycoplasma pneumonia #IDXposts
thelancet.com/journals/eclin…

Urinary tract infection (UTI) is one of the most common bacterial infections in the global community.

A Review in The Lancet Infectious Diseases aims to achieve consensus on a reference standard for UTI and increase homogeneity between studies: hubs.li/Q02qB-j00

🆕️🔥🔥ICYMI 🔴 Clinical Infectious Diseases
Vance Fowler
The 2023 Duke-ISCVID Criteria for Infective Endocarditis: Updating the Modified Duke Criteria
Follow me+Like it +Retweet it +DM me & I'll send you a link for full text✔️ #IDTwitter #IEwikiguidelines
academic.oup.com/cid/advance-ar…

Is de-escalation from echinocandins to azoles a safe strategy in patients with candidemia?
🆕️🔥Systematic review & meta-analysis evaluating the clinical outcomes of antifungal early DES (<7d) in Candida infections in a relatively large sample size
ijidonline.com/article/S1201-…

📢 🔥EMA CHMP recommends a new antibiotic for approval
Emblaveo (aztreonam-avibactam), indicated for treatment of cIAI, UTI,HAP & infections caused by certain types of bacteria that are resistant to other Abx & where patients have limited or no Rx options
ema.europa.eu/en/news/meetin…