The product of fantastic work & collaborations with Jianlong Wang Effi Kenigsberg Christina Curtis José A. Seoane Ana Rita Nobre Aplin Lab - Cancer Research Erica Dalla soledad sosa lab Emily Bernstein Lab Saul Carcamo Miriam Matthew D. Park Emma Risson Vivian Chua Jessica Teh Lena Wullkopf Melisa Lopez-Anton & others! Thanks all.

Overjoyed to see the work of this collaborative and collegial team out in print. Clinical trial matching, drug resistance, rare cancers, cancers w/o drivers: we've only scratched the surface of what can be discovered in AACR Project GENIE. Onward to 1 million!

“We only sample at the end” not any more! Christina Curtis showing how “evolution can be predictable”through use of high res sampling within enormous organoid evolutionary experiments #EACR2022 “initiating events are heavily intrinsic dependent” so let’s catch the horse before it bolts!

Great place to meet at the same time top speakers in cancer genomics, epitranscriptomics and machine learning. Vessela Kristensen RESCUER Oscar M Rueda José A. Seoane Nuria Lopez-Bigas Christina Curtis Marco Gerlinger

Frydman Lab Christina Curtis Dmitri Petrov Somatic evolution in cancer is different from germline evolution b/c somatic cells don’t undergo any recombination – they divide only by mitosis. As a result, all the mutations that accumulate in cancer remain completely linked through its entire cell lineage history. (2/11)

Chris Mason NanoString That was a pretty cool talk. Was impressed by the cell subtyping too

USC University Professor Emeritus Michael Waterman is the ' father of quantitative and computational biology'.

Learn more about how Waterman pioneered this research and movement! #ComputationalBiology #ComputerResearch news.usc.edu/199827/human-g…

Thank you to everyone who joined us--in person and virtually--at #BoG22 ; including organizers Christina Curtis, Hopi Hoekstra, MarioniLab and Jay Shendure and National Human Genome Research Institute, Oxford Nanopore and PacBio for generously supporting this meeting. See you at #BoG23 next May! bit.ly/BoG22

Absolutely delighted to share our new bioRxiv on experimental evolution in human TP53-deficient organoids biorxiv.org/content/10.110… - spearheaded by the amazing Kasper Karlsson in Christina Curtis lab 🥳 a project which started 5(!) years ago.. [1/x]

Ralph Weichselbaum Volastra Therapeutics Endpoints News Thank you very much Ralph!

Congratulations to LisaCoussens@CoussensLab, Ph.D., FAACR who was recently elected as AACR President! 👏 Among her many accolades, Dr. Coussens is a former V Scholar & Scientific Advisory Committee member. We're so grateful for her leadership and continued dedication to #cancerresearch !

Our experience w/GD2 CAR T cells in 4 patients with DIPG/DMG was published today. This work taught us much about how to safely & effectively treat this disease w/CARs. Deeply grateful to patients & families who bravely trusted us as we learned together.nature.com/articles/s4158…
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Applying to PhD programs this cycle and interested in Cancer Biology? Learn about our program during tomorrow's webinar!

There's still time to sign up - more info below. See you there! #AcademicChatter #phdlife